Effect of Vitamin B1 on Pain after Insertion of Intrauterine Device

Intrauterine device (IUD) has a wide use in qualified women to prevent pregnancy around the world. Pain is one of the main reasons why women avoid using copper intrauterine device continuously. So, strategies to reduce pain are necessary. The aim of this study was to determine the effect of vitamin B1 on the pain caused by intrauterine device insertion. This double-blinded, randomized controlled trial was performed on 126 women aged 18 to 35 years, referring to four public clinics in Boroujerd, Iran between 2011 and 2013. The women who experienced increased menstrual pain within the first cycle after IUD insertion were randomly divided into two groups: intervention group received vitamin B1supplement (100 mg) and control group received placebo one per day for three months during the second, third and fourth cycles after IUD insertion. Samples were evaluated within 5 months with one month interval before drug intervention (after IUD insertion), 3 months after drug intervention and then 1 month later after finishing intervention (without using drug and placebo). In this study, pain intensity was measured by Visual Analog Scale. (IRCT: 2012073010451N1) In contrast, pain duration mean in intervention group from 28.75±6.54 to 9.26±3.55 and in control group from 29.02±5.49 to 21.56±3.73 were reported (p<0.001). The mean of pain intensity in intervention group from 25.5% to 0% severe pain, and in control group from 24.3% to14.1% were reported. In intervention group (79.9%) and in control group (9.6%) no pain was reported (in the fifth month) (p<0.001).Need to analgesic drug in intervention group from 44.26% to 0%, and in control group from 38.7% to 42.8% were reported (p<0.001). The results showed that vitamin B1 is effective in reducing pain induced by IUD insertion.