Comparative study of anthropometric parameters in non-alcoholic fatty liver disease patients and healthy subjects

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease and obesity is a predictor of NAFLD risk in the general population. The purpose of this study was to examine the relationship between anthropometric parameters and obesity in NAFLD patients and comparison with healthy peoples. This case-control study was carried out on 94 patients with NAFLD and 100 healthy individuals. Body mass index (BMI) and waist to hip ratio (WHR) were measured in all participants. The Statistical analysis was performed using t-test and logistic regression model and P<0.05 was considered significant. The mean age of the patients was 43±12 years and 41.3±12.4 for control group. There was singnificant difference in Weight, BMI, waist and hip means between case and control groups (P<0.05). The mean of BMI was 28.6±5.4 and 25.2±4.5 in NAFLD and control group, respectively. Results showed that there was a significant association between Overweight (25 ≥ BMI< 30), obesity (BMI≥30) and NAFLD (P<0/001). Moreover, central obesity with odds ratio of 2.07, increased the risk of NAFLD (OR: 2.07, 95%CI: 1.1-3.7, P: 0.02). Threre are significant difference in anthropometric parameters between NAFLD patients and controls. Central and global Obesity is a major risk factor for NAFLD susceptibility.