The effects of the menstural cycle on the hemodynamic response to laryngoscopy and tracheal intubation in the elective head and neck surgeries

During menstural cycle in the follicular and lutheal phases arise multiple hormonal physiological and psychological changes. These alterations could change analgesics and anesthetics requirements. Preceding studies have marked the correlation between increased proges-terone level and hypersensitivity to pain. This study aimed to evaluate the effect of various phases of the menstural cycle on the hemodynamic response to laryngoscopy and tracheal intubation

This cross sectional study was performed on 68 patients. They were candidated for an elective head and neck surgery under general anesthesia with endotracheal intubation in Amir – Al – Momenin academic hospital in Rasht during 1390- 91. On the basis of the phase of the menstural cycle patients were divided into two groups follicular (5to 15th days) and lutheal (15 to 28 th days). Anesthesia protocol was similar in all patients. Heart rate، Systolic، Diastolic، Mean Arterial BP and Rate Pressure Product were measured in the baseline، immediately after intubation، 2 and 5 minutes after orotracheal intubation and the results were compared.

Age، ASA class and BMI were not significantly meaningful in two groups. The course of HR، SBP، DBP، MAP، RPP changes were considered which were not significantly statistically meaningfull.

This study defined that hemodynamic changes in response to laryngoscopy and intubations in follicular and lutheal phases were not significantly statistically meaningful.