Prevalence of qnr gene in clinical Acinetobacter isolates

Aims and This study investigated the prevalence of qnr genes and resistance to fluoroquinolone antibiotics among clinical isolates of Acinetobacter in Tehran. Prevalence of qnr genes among Acinetobacter isolates were determined by PCR technique. Also by the use of antibiogram method, susceptibility of isolates against the fluoroquinolone family of antibiotics, piperacillin-tazobactam, and colistin were examined. Evaluation of PCR in the 50 qnr-positive Acinetobacter isolates showed that 74% of them had qnrA and 22% had qnrB. Almost all of isolates were resistant to the fluoroquinolones. This study showed a high prevalence of qnr genes and a higher prevalence of genotype qnrA than qnrB.