Acute effects of coenzyme Q10 supplement on serum parameters of oxidative stress following one session of resistance training in male college athletes

The aim of this study was to investigate the effect of acute supplementary consumption of coenzyme Q10 on serum creatine kinase (CK) and lactate dehydrogenase (LDH) after a session of resistance exercise in male college athletes. Twenty male college athletes (mean age: 21±1.2 yr, weight:72 ± 8.1 kg, height: 177 ± 7.3 cm, body mass index: 23 ± 2.1 kg/m2), with at least six months exercise training in advance), were divided randomly into 'Q10 supplementation' and 'placebo' groups, randomly. Subjects received either of the following regimens, 120min prior to exercise; coenzyme Q10 (200 mg) or placebo (flour). All subjects performed a circular resistance exercise with 75% of one maximum repetition. CK and LDH concentrations were measured before supplementation and before and immediately after 24 and 48 hours resistance exercise. Results showed that CK concentration in Q10 group was significantly lower in the 3rd (Р=0.006) and 4th (Р=0.036) measurements, in comparison to placebo, while; changes in LDH did not show any significancy in all the measurements between the two groups (Р≤0.05). In conclusion, acute supplementation of Q10 had beneficial reducing effects on the CK production and oxidative damage after resistance exercise in male college athletes.