Remineralizing Effect of Topical NovaMin and Nano-Hydroxyapatite on Caries-Like Lesionsin permanant Teeth

NovaMin is a synthetic mineral composed of calcium, sodium, phosphorous and silica releases deposites of crystalline hydroxyl-carbonate apatite similar to tooth mineral composition. Furthermore, hydroxyapatite is a well known material for the remineralization of tooth enamel surface. The present study compared the efficacy of NovaMin and Nano-hydroxyapatite in the remineralization of carious lesions in permanent teeth. In an experimental in vitro trial, 30 impacted third molars teeth without any crack were selected and artificial carious lesions were developed on the teeth after exposing to demineralization / remineralizion cycles. The teeth were randomly treated with a NovaMin-contained dentifrice or nano-hydroxyapatite 2 minutes daily for a total 5 days and their Vicker’s microhardness values were calculated. The data were subjected to Student T and Mann-whitney U tests. The SMH was found to be higher in the teeth treated with NovaMin toothpaste (412.87kgf/mm2) than that in the teeth treated with NHA (388.40 kgf/mm2); however, this difference was not statistically significant. Both NovaMin-contained dentifrice and Nanohydroxyapatite solutions were effective to increase remineralization of carious-like lesions in permanent teeth.