Efficacy of Four Disinfectants against Hepatitis B Virus

Hepatitis B is an important infection in dentistry necessitating the use of disinfectants to prevent its transmission. This study compared the efficacy of 2/100 sodium hypochlorite disinfectants manufactured by four different manufacturers namely Ashimashi, Paknaz, Vitex and Active against hepatitis B virus (HBV). In this experimental laboratory trial, serum of 10 hepatitis B patients was poured into microtubes and Ashimashi, Paknaz, Vitex and Active disinfectants were added to them. Polymerase chain reaction (PCR) was performed with viral diagnostic kits to diagnose the virus genome. Real time PCR was performed before and after incubation with the disinfectants. The reductions occurred in the viral load of HBV were statistically analyzed by Kruskal-Wallis and Mann-Whitney U tests. No significant antiviral efficacy was noted following the application of Ashimashi 2/100 sodium hypochlorite disinfectant. Paknaz showed the highest efficacy against HBV. Vitex and Active ranked next with significant differences (P<0.0001). Under the study limitations, Paknaz 2/100 sodium hypochlorite solution was the most effective while Ashimashi 2/100 sodium hypochlorite disinfectant did not show adequate efficacy against HBV.