Smart gold nanosystems using for cancer diagnosis

Abstract:
Background and Objectives
The use of gold nanoparticles due to the medical field is expanding for special physical and chemical properties. So in this review we attempted to collect and review previous research into the diagnosis area.
Material &
Methods
This review is based on studies about gold nanoparticles in more than 100 papers in journals and written books on cancer until now. Accordingly 37 relevant cases were selected and studied. Resource selections were based on relevance to the topic, the research year, not duplicate, comprehensive resource and its contents. Keywords for this search were gold Nanoparticles, AU Nanoparticles, Cancer, Diagnosis, Drug delivery, Imaging, Protein respectively.
Results
The conducted studies indicate the current tendency toward use of gold nanoparticles is owing to the selective delivery capability, ease of access and low toxicity, allowing scientists to detect cancer at early stage within fewer time frames
Conclusion
Biofunctionalized gold particles are detectable in target organs and in vivo with microscopes. These improvements have made the nanoparticles detectable and increased their contrast , providing the ability to measure them easily. Because of the high density of electrons in the gold nanoparticles, images are of greater clarity.
Language:
Persian
Published:
Journal of North Khorasan University of Medical Sciences, Volume:7 Issue: 4, 2016
Pages:
745 to 759
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