Effects of 8 weeks of aerobic training on Agouti-related peptide, appetite hormones and insulin resistance in overweight sedentary women

The aim of this study was to investigate the effects of 8 weeks of aerobic training on Agouti-related peptide, appetite hormones and insulin resistance in overweight sedentary women.
Thirty overweight students (25≥BMI≤30) were selected and randomly divided: training and control. Before the start of practice period, and 48-hr after their last exercise session subjects completed the food frequency questionnaires. Then after blood sampling, their anthropometric characteristics were measured. The Training group participate in 8 weeks moderate intensity aerobic training while the control group continued their normal daily activities.
Agouti-Related Protein in the exercise group significantly increased (p=0.001). Significant changes were also observed between the two groups (p=0.005). While changes in leptin, insulin and insulin resistance were not statistically significant (P>0.05). Training leads to significant reduction in energy intake and fat (p=0.01) and carbohydrates intake (p0.05).
although 8 weeks moderate intensity aerobic training led to decrease in calorie intake, fat and carbohydrate consumption but this changes were not significant. Maybe, Agouti-Related Protein changes may affect factors other than appetite. Possibly, offering nutritional education and program along with exercise program can lead to more effective results.