Atrazine-Mediated Oxidative Stress Responses and Lipid Peroxidation in the Tissues of Clarias gariepinus

Fish have been at high risk of atrazine toxicity. Comparative atrazine toxicity on the tissues of Clarias gariepinus is scanty. Therefore, acute and chronic effects of atrazine on some biochemical parameters in Clarias gariepinus were investigated in this study.
Atrazine toxicity was determined by assessing the responses of glucose, protein, alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), superoxide dismutase (SOD), acetylcholinestarase (AChE) and malondialdehyde (MDA) in blood, gill and liver of fish exposed to both acute (0.00, 28.00, 30.00, 32.00 and 34.00 µg/l) and chronic (0.00, 7.00, 7.50, 8.00 and 8.50 µg/l) concentrations for 96 h and 28 d, respectively.
In acute exposure, glucose and MDA levels showed significant (P Exposure to varying concentrations of atrazine induced enzymatic/metabolic alterations in C. gariepinus. These alterations can be used as biomarkers of atrazine toxicity in fish.