Detailed study of the application of mass spectrometry in molecular biology

Mass spectrometry is a one of the most powerful techniques for identify of materials. This techniquemakesthe materials to be identified with the accurate determination of their mass. With the discovery of soft ionization techniques, this technique was entered into the field of molecular biology. So it was used for the identification of biological molecules. The introduction of mass spectrometry as an important research tool in biology and medical science and the introduction of several applications of this technique in these two areas are the main goals of this study. The method that was used in this study is the type of library research and this study was conducted on the basis of published articles in the past few decades. Latin articles related to the topic studied and the conclusions of them have been investigated. Mass spectrometry methods provide a unique opportunity for molecular specific analyses. This method has created a great development in detecting biological molecules. The molecules such as proteins, nucleic acids, oligosaccharides and lipides which constitute a main biopolymers of organisms are identified and analyzed by this method. Therefore, the study of molecular processes of the cell is possible. The high sensitivity and accuracy of mass spectrometry makes the development of new fields such as genomics, proteomics, lipidomics and metabolomics. Mass spectrometry has been widely used in molecular biology and researches in the field of proteomics is performedwiththe help of mass spectrometry.This method has an effective role in the understanding of molecular and functional mechanisms of the cell with identification of proteins and peptides and also with determination of molecular complexes.