Effect of Vitamin C on Serum Concentration of Brain-Derived Neurotrophic Factor among Healthy Inactive Young Men

The aim of this study was to investigate the effect of consuming vitamin C on the serum level of Brain-derived neurotrophic factor (BDNF) among healthy inactive young men.
In this semi-empirical study, 18 healthy inactive men were randomly divided into two groups; a group consuming vitamin C as a supplement and a control group. Subjects in consuming vitamin C group received 500 milligrams of vitamin C supplement daily for one week. The control group consumed placebo. Blood samples of participants were taken in fasting mode to measure BDNF concentration. BDNF was measured by ELISA method.
The serum levels of BDNF significantly increased one week after receiving vitamin C compared to the control group. In addition, the level of BDNF in subjects received vitamin C for one week significantly increased compared to the beginning of the investigation.
Data indicate that consuming vitamin C increased the serum concentration of BDNF in healthy inactive men.