Comparison the effects of ZnO nanoparticles and ZnO nanocomposites on Lipid Peroxidation in Rats

The purpose of this study was to compare the effect of Zinc oxide nanoparticles and Zinc oxide nanocomposites on serum lipid peroxidation in rats.
Fifty-sixadult male wistar rats were divided into 8 groups (7 rats in each group: one control group and six treatment group).Rats in treatment group received intraperitoneal injections of ZnO nanoparticles (10, 20 and 40 mmol/ml) and ZnO nanocomposites (10, 20 and 40 mmol/ml) for 28 days.Control rats received distilled water for 28 days. Serum lipid peroxidatin was assayed and compared with one-way ANOVA and tukey statistical analysis. Statistical significance was set at P Intraperitoneal injection of ZnO nanoparticles at 20 and 40 mmol/ml significantly decreased serum lipid peroxidatin in comparisonwith the control group (P ZnO nanoparticles aremore effective in reduction of lipid peroxidation in comparison with the ZnO nanocomposites.