Seroprevalence of IgG, IgM and IgA against Toxoplasma gondii in pregnant women in first trimester in northern Khorasan Province, Iran

Toxoplasmosis is a disease parasite which can infect human and animals. Infection in human is usually asymptomatic. The infection may be serious if is transmitted to the fetus during pregnancy. The present study aimed to determine prevalence and factors associated with T. gondii infection in northern Khorasan, Iran.
The cross–sectional study 1302 Serum samples were collected from different cities of Northern Khorasan Province and tested for IgG, IgM and IgA antibodies against T. gondii using ELISA method. Overall, 1302 pregnant women during first trimester were recruited. The mean age was from 16 to 46 years of olds and data were analyzed using the SPSS version 22.
From 1302 examined samples, 690, 40 and 57 samples were positive for IgG, IgM and IgA, respectively. In current work, there was not any significant difference between Toxoplasmosis and education level and use of row vegetables. But the differences between contact to cat and use of row meat and prevalences of toxoplasma gondii are significant.
The probability of T.gondii IgM and IgA contamination should seriously be considered during Pregnancy. Testing pregnant women for Toxoplasma gondii is suggested to be done routinely during pregnancy; especially in trimester.