Investigation of serum level ficolin-2 protein in patients with chronic obstructive pulmonary disease (COPD)

Chronic obstructive pulmonary (COPD) is one of the common and Progressive diseases, which microbial factors contribute to its development. There is a 50- 70% possibility that it may cause infection. Ficolin-2 protein moves to eliminate infectious agent by activating the innate immune system via complement. Therefore, In this study we examined the relationship between serum levels of Ficolin-2 and treatment duration in (COPD) patients.
In this study, the blood sample of 48 (COPD) patients and 30 healthy subjects that their blood and urine tests showed infection were taken, the control group. The serum levels of ficolin-2 protein were evaluated using ELISA method.
According to the research hypotheses (the relationship between the serum level and treatment duration and the relationship between lowness of serum levels and recurrence of disease) and the results of analyzes conducted by t-test in this study, there was a significant correlation between serum levels and duration of therapy in this disease.