Determination of existence of oqxAB genes in Klebsiella pneumoniae isolated from urinary tract infections and their antibiotic resistance pattern in Qom

Aim and the efflux pumps as one of the resistance mechanisms against antibiotics. So object of this study, is determining the existence of oqxA and oqxB gens in Klebsiella pneumoniae Isolated and their sample of antibiotic resistance.
the sample making of 500 referred outpatients to the laboratories of Qom province. For determining of antibiotic sensibility, it was according to instruction CLSI 2014. the existence of oqxA and oqxB genes was detected by PCR.

100 number of klebsiella pneumonie bacteria separated. Determined. all Klebsiella pneumonia were sensitive to Ciprofloxacin and Amikacin. The results out of PCR revealed 46% had oqxA gene and 52% had oqxB gene.

. Results out of present study suggest that the klebsiella pneumonia bacteria in strains isolated in hospitals of Qom has got a very significant statisics. Also, efflux pumps oqxAB have got a relatively high quantity.
The ways to confront and oppose antibiotic resistance including the efflux pumps oqxAB is important. These findings indicate the need to control the antibiotics treatments and to use new antibiotic agents for the treatment of infections caused by this bacteria and other resistant organisms.