A Comparison of the Effect of Eight Weeks Aerobic Training and Vitamin C Supplements Consumption on Antioxidant Enzymes in Men With Type 2 Diabetes

Aims: Type 2 diabetes is increasing as a common global health issue. The aim of this study was to investigate the comparison of the effect of eight weeks aerobic training and vitamin C supplements on antioxidant enzymes in men with type 2 diabetes.
In this semi-experimental study, 45 men with type 2 diabetes were selected by convenience sampling method. Were divided randomly into 3 equal groups: aerobic training with supplement, aerobic training with placebo and control groups. Aerobic training program included aerobic trainings up to 50-60 minutes at 65%-75% maximum reserve heart rate, three sessions per week which lasted for 8 weeks. Meanwhile, the supplement group took 100 mg of vitamin C before each training session. In this period, the control group did not take part in any physical activity. To make intra and between groups comparison, repeated measure (ANOVA) was used. For all statistical comparisons, the level of significance was set at pFindings: Eight weeks aerobic training with placebo and vitamin C supplements lead to a significant reduction in MDA and increase of SOD and CAT in men with Type 2 Diabetes. The average differences in the MDA, SOD and CAT levels have a statistically significant difference between the three groups.
Eight weeks of aerobic training, vitamin C supplements consumption and especially mix of them with together have similar affected on increase of antioxidant enzymes, prevents exercise-induced oxidative stress and thus type 2 diabetes. Therefore, it is recommended to use this method as an effective non-pharmacologic treatment method for prevention of adverse effects of an increased incidence of diabetes mellitus.