Water Drinking Test: Intraocular Pressure Changes after ‎Tube Surgery and Trabeculectomy

To study the effects of filtration surgeries (tube and trabeculectomy) on changes in intraocular pressure after a water drinking test.
In this prospective, non‑randomized, comparative clinical study, 30 patients, who underwent tube surgery, and 30 patients, who underwent trabeculectomy, were investigated; the patient were matched in terms of gender and age. Only one eye of each patient was included. The baseline intraocular pressure was ≤21 mmHg in all enrolled eyes with or without adjunctive topical medications. After the water drinking test, the intraocular pressure was measured and recorded at 15, 30, 45, and 60 minutes and the results were compared between the two groups.
In both groups, intraocular pressure significantly increased from baseline at all measured time‑points (P Intraocular pressure significantly increased after the water drinking test in both groups. Intraocular pressure started to decline 30 minutes after the water drinking test in the trabeculectomy group, while it continued to increase up to 60 minutes in the tube group. This finding may have implications regarding the efficacy or safety of the procedures in patients with advanced glaucoma.