Therapeutic effect of honey, methanolic extracts of garlic, walnut leaves,thyme and yarrow on mouse model of cutaneous leishmaniaBalb/C

Leishmaniasis is a protozoan parasitic infection that is reported in most parts of the world and is prevalent in different parts of the world. The disease is the third most important disease in the world transmitted through the biological vector. From 12 to 15 million people in many countries around the world are infected with leishmaniasis and every year there are 2 million new cases of leishmaniasis worldwide. Treatment with chemical drugs may have a lot of side effects for the patient. For herbs, garlic, walnut leaves, honey, thyme, and yarrow, there is a significant therapeutic effect. In the present study, products from medicinal herbs and honey for the treatment of cutaneous leishmaniasis were investigated in the Balb/C mice model. The results of this study showed that garlic extract at concentrations of 25, 50 and 100 mg/mldid not any statistically significant therapeutic effect on leishmania, and there was no statistically significant difference between the controls (p≥0.05). Walnut leaf extracts showed significant therapeutic effects. Also, honey extracts at different concentrations had a significant therapeutic effect and showed a lower effect on the extract of walnut leaves. Yarrow and thyme extracts also had good therapeutic effects on the walnut leaves and honey. Thyme extract with a 100mg/ml therapeutic effect had a favorable therapeutic effect. The results of this study might be effective in the treatment of leishmaniasis.