Importance of myocardial strain versus aortic stiffness in echocardiography in estimating the extent of coronary stenosis in angiography.

Coronary artery disease (CAD) is the leading cause of death in adults. Aside from history and physical examination, noninvasive tests are increasingly used to determine the presence of CAD. The aim of this study to was to detect whether myocardial strain and noninvasive aortic pulse wave velocity (PWV) analysis could be helpful in non-invasive assessment of extent of CAD. In this cross-sectional study, 52 Patients were enrolled, assessed with echocardiography in a day before coronary angiography. Global longitudinal strain (GLS) and Aortic PWV were measured in echocardiography. Coronary artery stenosis was calculated in angiography. The statistical relationship between the presence and the extent of coronary stenosis, measured by PWV and strain reviewed and evaluation of the conformity of these two methods was compared with angiographic findings. Of the 52 patients enrolled in this study, 37 were males (71.15%) and 15 were females (28.85%). Only GLS showed significant difference between two groups (normal coronary arteries or non-significant lesion versus significant CAD) in all three vessels (p value in LAD=0.03, LCX=0.04, RCA=0.03). Otherwise, PWV did not show any significant difference. Of 52 patients whom enrolled in this study, 37were male (71.15%) and 15 were female (28.85%). Only GLS showed significant difference between two groups (normal coronary arteries or non-significant lesion versus significant CAD) in all three vessels (p value in LAD=0.03, LCX=0.04, RCA=0.03). Otherwise ,PWV did not. In patients with suspected CAD, GLS assessed by 2D-STE at rest could be a predictor of significant coronary artery diseases. In contrast, arterial stiffness, measured noninvasively thorough PWV, did not appear to be an independent factor in this context