Protective Effect of Aerobic Training along with Punica granatum L on Cardiac Injury Biomarkers in Women with Type 2 Diabetes

  The most common and clinically important complication in adults with diabetes is cardiovascular diseases (CVDs). Exercise training and pomegranate have been recognized to ameliorate CVDs. The aim of this study was to examine the protective effect of aerobic training along with pomegranate juice concentrate on cardiac injury biomarkers in women with type 2 diabetes. In this study, 33 women with type 2 diabetes were selected from Babol City and were randomly divided into four groups (control, pomegranate concentrate, training and pomegranate concentrate+training). The training groups participated in a progressive aerobic training for six weeks, three sessions a week (60% to 75% of reserved heart rate and for 25 to 45 min). The groups of pomegranate concentrate and pomegranate concentrate+training were provided 150 mL of pomegranate juice concentrate for six weeks (at about 18 p.m). Two days before and after the protocol, their blood samples were taken in fasting state. The results showed that Troponin T, CK-MB and LDH were decreased significantly in the experimental groups (p=0.000, p=0.014 and p=0.034, respectively), whereas significant reduction of Troponin I and CK was observed only in the pomegranate concentrate+training group (p=0.048 and p=0.041, respectively). It seems that aerobic training and pomegranate juice concentrate and combination of both reduce cardiac injury biomarkers in women with type 2 diabetes