Concurrent incident of oral lichen Planus and hyperthyroidsm and hypothyroidism

Lichen planus is a mucocutaneus disorder with oral complications such as ulceration, soreness, and discomfort and malignancy transformation risk. Previous studies on the relationship between oral lichen planus (OLP) and thyroid problems had inconsistent results. Considering the importance of the subject, the purpose of this study was to investigate this relationship. This cross-sectional study was performed on 12,000 records in the Archives of Shahid Sadoghy Dental Faculty (Yazed, Iran) from 2004 to 2014 with convenience sampling method. The patients were divided into four groups, based on OLP and thyroid disease. Correspondingly, inclusion criteria included 18-60 years of age, the absence of other systemic and mucosal diseases and other thyroid diseases (other than hypothyroidism or hyperthyroidism). Among 542 subjects included in the study, 31.4% of patients with hypothyroidism and 37.5% of hyperthyroidism patients and 20.8% of the normal people were diagnosed with OLP. No significant relationship was found between thyroid disease and patients with OLP and also between lichen planus and sex. However, the relationship between age and OLP was significant increasing by 1.7 times for each year. In this study, there has not found any significant relationship between OLP and thyroid disease and sex, but increasing age had a clear effect on the risk of OLP. Considering the significance of both diseases, other studies with more sample sizes are recommended.