ACTN3 Genotype and Some Athletic Performance Variants of Non-Athletic Adolescents Boys of Urmia

Developed countries have presented a better plan for evaluating the frequency of genes related to sport performance in order to promote the goals of championship sports of the community, but less research has been done in developing countries. Accordingly, the aim of this study was to investigate ACTN3 gene polymorphism and some athletic performances of non-athlete male adolescents of Urmia. The subjects of the semi-experimental study were 123 healthy non-athletic boys who were in the second stage of Tanner's maturity. DNA genome of SALIVA was extracted using a suitable kit and the study of polymorphisms was performed by PCR- RFLP method. In order to compare the mean of different exercise performance, at first the subjects were categorized based on three types of ACTN3 polymorphism, then the means of exercise performance of the three groups were separately compared with one-way covariance analysis (ANCOVA). The significant level of p<0.05 was considered. The findings of this study showed that genotype XX has a significant effect on the endurance function, but genotypes ACTN3 does not have the significant effect on the speed and strength performance of subjects. The results of this study showed that despite the effect of genotype XX on the endurance performance, this gene polymorphism cannot be considered as a determinant factor in speed and strength performance.