A survey on fungi colonization prevalence in patients with chronic peptic ulcer diseases

Prolonged antiacid and antibiotic usage in peptic ulcer diseases mayPredispose fungi colonization in stomach., detect and eradication of it may prevent delayed treatment. In order to isolate and diagnosis of fungi infestions in patients with gastroduodenitis and gastric ulcer This study has been planned..

This is a prospective crossectional study. We studied140 biopsy specimens of patients with chronic peptic ulcer diseases (morthan12 month) referred to Qum province hospitals, during 8 month. The biopsies selected for 1: direct examination with KOH10%.2: culture of specimens3: tissue staining with H&E

7.1% cases of yeasts were isolated in this investigation. Isolated yeastshave been identified as follows: 10 cases of C.albicance7.1% of The patients were male and the rest were female.

All the patients that had a positive history of long lasting antacid taking for gastric ulcer or gastritis. Candidacies must be investigated. duodenitis and gastric ulcer, who are refractory to classic therapies and also in patients Who have the chronic disease, fungi infestations must be roll out.