Effects aqueous extract of thyme Thymus vulgaris L on blood biochemical parameters and liver tissue in rats under immobilization stress

Stress has different adverse effects on the biological processes of living organisms. Therefore, replacing herbal medicines with fewer side effects in the treatment of diseases and improving health is the most important. In this study the effect of aqueous extracts of thyme on blood biochemical parameters and liver tissue in female rats under immobilization stress were studied. In present experimental study, 24 adult female Wistar rats in weight range of 173±12 g were randomly divided into four groups of six rats in each: group1, Control, group2, the group immobilized stress, groups 3and 4, groups to immobilized stress by oral prescription extract of thyme the doses of 100 and 400 mg/kg respectively. At the end of the studies, serum cholesterol, LDL and HDL and MDA, TAC in liver tissue homogenates were estimated. The results indicated significant reduction in the level of cholesterol, LDL, MDA in treated groups with aqueous extract of thyme and a significant increase in HDL, TAC. The extract of Thymus vulgaris L be due their antioxidant can partly reduction the serum level of cholesterol, LDL and liver tissue protection against the damaging effects of immobilization stress.