Comparison of high-intensity interval and continuous training effects on plasma levels of fibrinolytic factors in CAD patients

The degradation of fibrinolysis is considered as a very important pathogenic factor in FULL NAME (CAD) progression and different exercises improve the function of the fibrinolytic system in these patients in various ways. This study surveys the effects of two types of high intensity interval and continuous training on some fibrinolytic factors of CAD patients. Subjects and

A total of 30 volunteered eligible patients divided into three groups of interval or continuous training and control group and exercised for 12 weeks, 3 sessions per week. Changes of TAFI anti-gene and the tPA/PAI-1 complex were analysed by covariance test before and after the training period.

There was no significant differences in changes of TAFI anti-gene between control and interval group as well as control and continuous group (P>0.05) but the t-PA / PAI1 complex in both interval groups (P=0.001) and continuous (P=0.001) had a significant decrease regarded to control group. Decrease of the TAFI anti-gene was significantly more than the continuous group (P=0.028), however, the reduction of t-PA / PAI-1 complex was significantly more than the periodic group (P = 0.024).

The results showed that that both of the interval and continuous training creates desirable effects in the fibrinolytic system of CAD patients through separate mechanisms. It can be concluded that applying both types of these two exercises is essential for improving performance of this system.