The effect of eight-week combined exercise training (resistance-endurance) and Omega-3 ingestion on the levels of fetuin-A and metabolic profile in obese elderly women

Fetuin A is secreted by different tissues including liver and adipose tissue and affects the function of different body tissues. The aim of the present study was to investigate the effect of eight-week combined exercise training (resistance-endurance) and Omega-3 ingestion on the levels of fetuin-A and metabolic profile in elderly obese women.
 
In a semi-experimental research, 40 elderly obese women (average age of 65.74±3.83 years old, body mass index 32.5±1.0 kg.m2) were assigned to four groups including placebo, Omega3, training and training+Omega3 groups. Combined exercise training (resistance-aerobic) was conducted for eight weeks and three session per week and each combined training session consists of resistance and aerobic training. The subjects in Omega3 and training+Omega3 groups consumed daily 2000 mg of Omega 3. Blood sampling was conducted in pre and post (two days after last combined training session) stages and fetuin A level was measured by Elisa method. Data was analyzed by covariance test.
 
Present study results indicated that fetuin A level significantly decreases in training and training+Omega3 group compared to placebo and Omega3 groups (p<0.001) and these changes were associated with improvement of lipid profiles.
 
Probably, a decrease in fetuin A level is part of positive effectiveness pathway of combined training in improving metabolic profile in elderly obese women.