Polyotropic effects of vitamin D on health and disease

Vitamin D is a fat-soluble vitamin, which has been well known for its role on calcium and phosphate homeostasis since many years ago, but several studies in recent years have shown that vitamin D is involved in a variety of other processes which can be included its role on the immune system and the related diseases. In this article, the most recent findings about the role of vitamin D in the immune system and a number of immune-related diseases have been investigated. Reviewing the articles shows that vitamin D and its receptor have an important role in the function of the body immune system. It seems that screening of vitamin D levels in the society can play a useful role not only in the preventing certain diseases and cancers but also in reducing the severity of the disease and better responding to common treatments.