Coronary artery bypass graft surgery combined with cardiopulmonary bypass causes changes in body physiology. In the meantime, aortic cross clamp time and cardiopulmonary bypass have been implicated in surgical outcomes. The purpose of this study was to determine the association between mean duration of aortic cross clamp opening to end of cardiopulmonary bypass with surgical outcome of patients after coronary artery bypass graft surgery (CABG).
This was a descriptive cross-sectional study on 47 patients with age range of 40 to 65 years who underwent CABG surgery in Shahid Chamran hospital, Isfahan, Iran; they were selected using non-random sampling method over a 5-month period in 2019. In these patients, the aortic-clamp opening period was measured until the end of cardiopulmonary bypass, and evaluated for surgical outcomes such as death, atrial fibrillation, mechanical ventilation time, troponin and creatine kinase-MB (CKMB) levels before surgery, and 12, 24, and 48 hours after it, as well as the length of intensive care unit (ICU) stay.
There was no significant relationship between the mean duration of aortic cross clamp opening to end of cardiopulmonary bypass with death, atrial fibrillation, preoperative and 12, 24, and 48 hours postoperative CKMB level, and ICU stay. Moreover, there was a significant relationship between this time period and preoperative and 12, 24, and 48 hours postoperative troponin levels and the duration of lung mechanical ventilation.
Extending the interval time of opening aortic cross clamp ton the end of the cardiopulmonary bypass, raised the mechanical lung ventilation time. By reducing the duration of this interval, the duration of mechanical ventilation and postoperative pulmonary complications can be reduced.
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