The Effect of Continuous Training Course Exercises and Resveratrol Supplementation on Serum BDNF and GGT in Male Rats

Continuing training programs can improve sport performance. However, these exercises can cause pressure on the hormonal and metabolic systems. Resveratrol might be effective on the improvement of the alterations induced by continuing training. The present study investigated the simultaneous effect of resveratrol consumption and continuous exercise on BDNF and GGT. 

In this experimental study, 24 rats were randomly divided into the 2 groups of continuous exercises, and resveratrol supplement + continuous exercises. Resveratrol solution was administered to the resveratrol + ontinuous exercises group for 8 weeks, each day 8 mg per 100 g of the body weight. The treadmill continuous training program was carried out for 8 weeks. At the end of the course, blood was obtained for measuring the indices of BDNF and GGT. These indices were analysed by  SPSS software, version 22.

The results indicated the higher mean of GGT and the lower mean of BDNF in the continuous training + resveratrol compared to the continuous exercises group. The use of resveratrol caused a significant increase in BDNF (P = 0.007) and GGT (P = 0.06) in the continuous training+ resveratrol group.

The results of the present study showed that continuous exercise + resveratrol consumption were effective on controlling and improving the indices changes in BDNF and GGT.  The simultaneous effect of supplementation and exercise increased the metabolic, neurological and protective opposite effects