Considering tourism industry and the factors affecting its spread for achieving its economic benefits has done the researches on identification of factors affecting the tourism industry quite necessary. The industry needs to develop one of the most important information tools of Information and Communication Technology (ICT) has caused examine the relationship between the two variables is the main goal of this study. Tourism industry has been considered as sustainable industrial in the third millennium, because of the economic context of globalization attracted economic policies. Improvement of Information and Communication Technology (ICT) has been caused the tourists to check and assess the condition of their travel destinations before traveling. The article explained the effects of ICT, Globalization, Reel per capita gross domestic product and Human capital variables on tourism industry performance by panel regression method in the period 2003-2012 in 28 selected countries. According to the results, all variables are affecting tourism industry positively. So, to clarify and improve the performance of the economy, ICT expansion is suggested