Survey on immunogenicity effcacy of a dual vaccine,Combined Rev. 1 and Sheep Pox Vaccine

The diseases, brucellosis and sheep pox, are endemic in Iran and they cause serious losses to the production andhealth of livestock. Susceptible livestock have been vaccinated against these two diseases in appropriate seasonswith a vaccine from Razi Institute vaccine for several years. But these diseases, especially the dangerous zoonosisbrucellosis, have not been eradicated after all these years. In this case-control study, 40 lambs within the age rangeof 3.5 - 6 months were selected from a native sheep flock. Vaccines and materials used in this survey were obtainedfrom Razi Institute. This study revealed that the administration of dual vaccine contained of bacterial vaccinesFDRev. 1 with sheep pox vaccine with one injection produced antibody titration as the same as FDRev.1 vaccineseparately. It would be cost beneft to conduct this research for the whole country as it will save lots of money inthe context of staff administration and vaccination. It can also decrease the side effects of multiple vaccinationssuch as stress.