The Effect of Circuit Resistance Training on Cardiotrophin-1 and Platelet in Active Body Building Men: A Clinical Trial Study

Cardiotrophin-1 is a member of interleukin 6 family, causes cardiac hypertrophy and with platelets is involved in heart atherosclerosis. Circuit resistance training is part of athleteschr('39') body building training. So, the aim of the study was to investigate the effect of circuit resistance training on cardiotrophin-1 and platelet in active bodybuilding men.

The participants of this experimental study were 30 active male bodybuilders (age: 24.95 ±1.49 years) in Ardabil in 2019 who were randomly divided into two groups of exercise (n=15) and control (n=15). Subjects in the experimental group completed a circuit resistance training session including 10 stations (leg press, chest press, barbell curl, frontal pull down, front leg, parallel, back pull down, cable pulley row, barbell shoulder press and back leg) with 40-60 one repetition maximum, 15 seconds at each station, and a 45-second interval rest between stations, in addition to their normal body building exercises. The control group performed their normal bodybuilding exercises. Independent and dependent t-tests were used to compare the intergroup and intragroup changes of cardiotrophin-1 and platelet, before and after training.

Cardiotrophin-1 increased significantly after resistance training compared to before exercise (p<0.001) and also compared to the control group (p<0.001). Platelet increased significantly after resistance training compared to before exercise (p<0.001) and also compared to the control group (p<0.001).

According to an increase in cardiotrophin-1 and platelet after circuit resistance training, it is recommended that coaches and athletes cautiously start performing circuit resistance training for maintaining athleteschr('39') health and reducing thrombosis.