The Incidence and Factors Associated with Major Congenital Malformations Recorded in Newborns Born in Chaharmahal Va Bakhtiari Province in 2016

Congenital malformations are one of the causes of infants disability and death. this study was performed to determine the incidence of major congenitals anomalies and their relationship with some related factors at birth.

In this cross-sectional study, all newborns born in hospitals of Chaharmahal va Bakhtiari province were evaluated for major congenital malformations at birth. information recorded in the case file including parent and infant characteristics was extracted from the mother and infant system. data were analyzed using Generalized Linear Model, family (poisson).

Of the 19666 newborns studied, 63 (3.2 per 1,000) had major congenital malformations at birth. in the crude model, pregnancy age, neonatal birth weight, neonatal height, and neonatal head circumference variables were significantly associated with congenital malformations. but in adjusted model 1, residence was significantly related to the incidence of congenital malformations and in adjusted model 2, the incidence of congenital malformations was related to neonatal pregnancy age, neonatal birth weight and neonatal head circumference.

Some of MCAs with early diagnosis and treatment can prevent disability. Therefore, the emphasis on public education to consider appropriate gestational age, proper nutrition before and during pregnancy, emphasis on prenatal and prenatal care is necessary to prevent congenital anomalies.