An overview of genetic findings in the allergic rhinitis disease

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Introduction

Allergic rhinitis is a more prevalent health disorder in all regions of the world. In recent years, the study on Allergic rhinitis because of its higher prevalence and its effect on development of asthma have been more attended. In this article specifically reviews Singlenucleotide polymorphism studies in allergic rhinitis disease.

Materials and Methods

In this study, the results of previous research conducted between 2005 and 2020 in the field of genetic susceptibility to allergic rhinitis have been used. Articles were collected by searching keywords Allergic rhinitis, genetic polymorphisms, single nucleotide polymorphism in the databases Scopus, Google Scholar, PubMed, Science Direct.

Results

In these studies, the candidate genes and the variants of single nucleotide polymorphism associated with allergic rhinitis have been investigated. The data collected in this study are the result of studies conducted in different parts of the world. The population of studies in these articles were allergic rhinitis patients.

Conclusion

Results showed association of several SNPs of various genes in allergic rhinitis that some of them may be useful incomprehension of AR pathophysiology finding new procedures for allergic rhinitis immunotherapy

Language:
Persian
Published:
Journal of Sabzevar University of Medical Sciences, Volume:27 Issue: 6, 2021
Pages:
770 to 775
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