Comparison of Choroidal Thickness in Psoriasis and Control Groups Using Optical Coherence Tomography

One of the most common extracutaneous complications in psoriasis patients is ocular complications, which is controversial concerning its effect on choroidal thickness. This study aimed to compare the psoriasis patients with healthy individuals in terms of the thickness of the choroidal layer using the optical coherence tomography technique.

In this case-control study, 30 psoriasis patients were compared with 32 healthy individuals who were matched for gender and age. Choroidal thickness was measured in both groups using the optical coherence tomography technique. Furthermore, the relationship of the choroidal thickness with the severity and duration of the disease was assessed in patients.

The mean choroidal thickness of the left eye (312.1±12.0 mµ vs. 296.3±20.8 mµ), right eye (310.6±12.5mµ vs. 297.5±17.5mµ), and regardless of the left or right eye (311.3±12.2 mµ vs. 296.9±19.1mµ) was significantly higher in patients, compared to the control group (P=0.001 for all three mean values). No significant relationship was found between disease duration and severity with choroid thickness. Moreover, the patients with multiple limb involvement had a higher mean choroid thickness; however, it was not statistically significant.

According to the results of the present study, patients with psoriasis have a greater choroidal thickness, compared to healthy individuals, which is not related to the severity, type of involvement, and duration of the disease.