The effect of ACE and ACTN-3 difference genotypes on fundamental movement skills development in 4-6 years old children

 The identification of effective factors on fundamental movement skills, considered as the substructure of advanced movement skills, can be very important in superior sports talents’ identification and guidance. Therefore, the aim of this study was to investigate the effect of ACE and ACTN-3 genotypes on the development of fundamental movement skills in children. The statistical population of this study included 4-6 years old kindergarten children in Aleshtar and 50 of them were selected, using cluster sampling method, as the study samples. The data collection tools included the test of gross motor development (TGMD-2) and PCR for determination of ACE and ACTN-3 genotypes. A one-way analysis of variance and independent- t test at a significance level of p≤ 0.05 was used to analyze the study data. The findings showed that the D-allele of ACE carriers, (DD or ID genotype), had greater development of locomotors movement skills than II genotype carriers (p<0/001), and also ACTN-3 R-allele carriers (RR or RX genotype), had greater development of locomotors movement skills than XX genotype (p<0/000). However, none of these differences was observed in the development of object control motor skills (p> 0.05). Therefore, it can be said that the children carrying DD or ID genotype of ACE and RR or RX genotype of ACTN-3 had higher development level in locomotors motor skills performance and will be able to perform sport skills in higher levels if provided with desirable environmental conditions.