Psychometric Properties of the Pediatric Quality of Life InventoryTM Version 3.0 Cardiac Module in Iranian adolescent with Congenital Heart Disease

This study aimes to investigate the psychometric properties of the pediatric health-related quality of life inventory (PedsQLTM 3.0 Cardiac Module) in Iranian adolescent with congenital heart disease.

After linguistic validation, the Iranian version of PedsQLTM 3.0 Cardiac Module was completed by 180 adolescent with congenital heart disease, aged 13-19, and their parents, who referred to the echocardiography section of the Rajaei Cardiovascular, Medical and Research Center (RCMRC) for a cardio checkup in July-September, 2018. In addition to PedsQLTM 3.0 Cardiac Module, the general version of pediatric quality of life inventory (PedsQLTM 4.0 Generic Core Scales) and the anxiety section of Child Symptom Inventory (CSI-4) were used to investigate the convergent and divergent validity of the PedsQLTM 3.0 Cardiac Module.

Exploratory Factor Analysis (EFA) indicated 6 factors for child self-report and 7 factors for the parent proxy-report of PedsQLTM 3.0 Cardiac Module. Moreover, the results showed an acceptable positive significant correlation between PedsQLTM 3.0 Cardiac Module and PedsQLTM 4.0 Generic Core Scales and an acceptable negative significant correlation between PedsQLTM 3.0 Cardiac Module and the anxiety section of CSI-4. Furthermore, the Cronbach Alpha for all dimensions of PedsQLTM 3.0 Cardiac Module (adolescent self-report and parent proxy-report) was reported as (α =0.34 to α =0.89) and (α =0.44 to α =0.91), respectively. Likewise, the test-retest correlation for all factors, except for the medication intake problem in adolescent self-report, was higher than α =0.70, which indicates its stability over time. Moreover, the correlation between adolescent and their parents’perception of the adolescent’s quality of life was low to mediocre (P ≥0.01) in all dimensions except for the communication.

Altogether, the results of the study support the validity and reliability of PedsQLTM 3.0 Cardiac Module in Iranian population to be applied for future uses.