The Effect of Q10 Supplementation on Lipid and DNA Degradation IndicesFollowing an Acute Physical Activity

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Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background and Objectives 

The use of antioxidant supplements improves and reduces oxidative stressfactors following intense intense exercise. Exhaustion was performed in female athletes.

Subjects and Methods

14 female athletes with an age range of 20 to 28 years and a maximum oxygenconsumption of 42-52 m/kg/min in a quasi-experimental design randomly divided into two groups receivingcoenzyme Q10 supplementation and placebo (5 mg/kg body weight). Were. After 14 days ofcoenzyme Q10 supplementation, the subjects performed an intense, debilitating activity. Urine sampleswere collected in three stages (baseline, before and 24 hours after exhaustive activity) to determine theconcentration of 8-OHdG and MDA.

Results

There was a significant difference of 62% in the increasing response of urinaryOHdG-8 to an exhaustingaerobic exercise session (P = 0.003). However, the 2% difference in the increasing urinary MDAresponse of the supplement and placebo groups was not significant after the last quasi-competitiveaerobic training session (P = 0.7).

Conclusion

According to the results of the study, two weeks of high-pressure aerobic training causesDNA damage and lipid peroxidation in female athletes, and supplementation with Q10 helps preventthe 8-OHdG response of female athletes after a strenuous high-pressure aerobic training session andreduces DNA damage. Become athlete

Language:
Persian
Published:
Jundishapur Scientific Medical Journal, Volume:20 Issue: 5, 2022
Pages:
474 to 485
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