Evaluation of Cognitive Dysfunctions in Patients with Type 1 Bipolar Disorder with Psychotic features in Comparison with the Control Group

Bipolar disorder affects an individual’s mood, energy, and routine life activities. This disorder is associated with dysfunctions in cognitive and executive function and influences different aspects of one’s life. attention, verbal learning and executive function are domains affected the most in bipolar disorder. Also, more neurocognitive dysfunctions in verbal memory, working memory, visuospatial abilities and some aspects of executive functions including planning, working memory, processing speed, psychomotor speed and sustained attention among patients with psychotic features is reported. The aim of this study was to investigate the cognitive dysfunctions of patients with type 1 bipolar disorder with psychotic features in comparison with the control group. In this regard, by a causal-comparative study, a sample selected by convenience sampling method included 45 patients with bipolar disorder and 54 subjects as the healthy control group and their cognitive function were assessed. The results of multivariate analysis of variance indicated significant differences between the two groups in terms of the cognitive functions of memory, attention, intelligence, and cognitive inhibition. Results of this study supports this finding that bipolar disorder is associated with cognitive profile difficulty in comparison with normal control group.