The effect of combined training on coupeptin and insulin resistance in obese women with poly cystic ovary syndrome

The aim of this study was to evaluate the effect of combination exercises (aerobic-resistance) on coupeptin and insulin resistance in obese women with polycystic ovary syndrome. In this quasi-experimental study, which was performed with a pre-test-post-test design, 28 obese women with polycystic ovary syndrome ranging in age from 20 to 35 years were randomly selected and divided into 2 groups of 15 combined and control exercises. Blood samples were collected in two stages of pre-test and post-test (after 8 weeks of training). The training protocol consisted of 2 weeks of combined exercises that were performed three sessions per week in two sections of rope training and resistance training with elastic. Data were analyzed by analysis of variance with repeated measures. The results showed that combined exercise significantly increased the coupeptine of obese women with polycystic ovary syndrome (P <0.05). Other results also showed that combined exercise significantly reduced insulin resistance in obese women with polycystic ovary syndrome (P <0.05). Overall, the present results suggest that obese women with polycystic ovary syndrome may be able to prevent the inflammatory stress caused by exercise and its aftermath by using combined exercise.