Remineralization potential of four Iranian toothpastes on initial carious lesions in primary teeth

Daily use of toothpastes are one the most common routes of dental caries prevention. The aim of this study was to evaluate the efficacy of four Iranian fluoridated toothpastes on remineralization of incipient caries lesions in primary teeth.

In this experimental study, a total of 60 sound primary anterior teeth were randomly divided into 6 groups of 10 teeth each: 1) Pooneh toothpaste, 2) Nasim toothpaste, 3) Crend toothpaste, 4) Irox toothpaste, 5) Oral B toothpaste, and 6) Negative control. Enamel microhardness (EMH) was measured in all samples at the baseline, after demineralization, and after 28-day remineralization. All data were analyzed by one-way ANOVA test. All tests were performed at a 5% level of significance.

EMH values decreased significantly in all groups after demineralization. The mean microhardness values after demineralization were not significantly different in intervention groups (p= 0.45). The remineralization process significantly increased microhardness in all groups (p <0.04). The mean microhardness values in Oral B toothpaste group were significantly higher than Crend, Nasim and Irox toothpaste groups (p = 0.012, 0.018, and 0.009, respectively), but there was no significant difference between Oral B and Pooneh toothpaste group (p = 0.216). Crend, Nasim, Irox toothpastes did not show significantly different EMH values.

In this study, all fluoridated Iranian toothpastes increased microhardness of demineralized enamel surface. However, the efficacy of Oral B and Pooneh toothpastes for remineralizing of demineralized primary tooth enamel was greater than Crend, Nasim and Irox toothpastes.