The Effect of Aerobic-Resistance Training Course on Plasma Levels of Neuroglin 1 and Interleukin 6 in Patients with Coronary Artery Bypass Graft

Coronary artery disease is currently one of the leading causes of disability and death worldwide. The present study aims at investigating the effect of eight weeks aerobic-resistance training on neuroglin-1 and interleukin-6 in patients with coronary artery bypass grafting. The research method was quasi-experimental and pre-test-post-test. The statistical population was all patients with coronary artery bypass grafting in Mashhad. Height 1.58 ± 0.03 (m), weight 68.11 ± 5.54 (kg), body mass index 27.18 ± 2.47 (2 kg / m2) and disease history 8.75 ± 25/20 (month) was formed after coronary artery bypass surgery. According to the inclusion criteria, they were divided into experimental (12) and control (12) groups. Data was analyzed using independent t-test and paired t-test at the significance level of P≥0.05 and SPSS software version 21. The results of the present study showed that eight weeks aerobic-resistance training increases neuroglin1 (P = 0.001) and insignificantly decreases interleukin 6 in the combination training group compared with the control group (P = 0.061). Statistical results of t-correlated t-test showed a significant increase in neuroglin1 (P = 0.001) and a non-significant decrease in interleukin 6 in the post-test combination test group compared with the pretest (P = 0.889). These changes were not significant in the control group (P = 0.331, P = 0.789. The data of the present study showed that aerobic-resistance training can improve the condition of patients with coronary artery bypass graft by increasing the studied factors.