Comparison of intraoperative administration of ketorolac and morphine in postoperative pain control in septorhinoplasty patients: A double-blind randomized clinical trial study

Septorhinoplasty surgery is one of the most well-known cosmetic surgeries among ear, nose and throat surgeries. Postoperative pain is still one of the most important factors affecting patient satisfaction. These symptoms can be uncomfortable for the patient. The purpose of this study is to compare the intraoperative administration of ketorolac and morphine in controlling postoperative pain in septorhinoplasty patients.

The present study is a double-blind randomized clinical trial that was conducted during a six-month period from March 2022 to August 2022 in 180 patients referred to the operating room of Motahari Hospital in Jahrom city who underwent septorhinoplasty surgery. Patients were randomly divided into three groups of morphine 6 mg and ketorolac with doses of 30 and 60 mg. Information collection tools include; Age, gender and pain level after surgery. Pain intensity was measured by pain measurement scale (VAS). Data analysis was done using spss version 21 and descriptive statistics (mean and standard deviation) and inferential statistical test (Fisher).

In terms of gender, 67.22% of the participants were male and 32.77% were female. The distribution of the number of men and women in the study groups was not significantly different (P=0.80). There was no significant difference between the study groups in terms of age (P=0.14). In terms of felt pain, Fisher's statistical test showed that more people in the ketorolac 30 mg group had felt pain than the other two groups, which was statistically significant (P=0.003).

Due to the importance of reducing the pain of patients after surgery and minimizing the side effects of surgery, it is possible to use Ketorolac at a dose of 60 mg during septorhinoplasty surgery to control pain due to the lower side effects of Ketorolac compared to morphine Used after surgery.