The effect of TRX training on nitric oxide and homocysteine levels as indicators of vascular endothelial and inflammation in inactive obese women

  Recent studies suggest that obesity plays an effective role in the occurrence of inflammation; on the other hand, inflammation can affect on function of vascular endothelium. High levels of homocysteine ​​can lead to inflammation and vascular endothelium damage. Nitric oxide is also considered as one of the influencing factors on endothelial function. The present study was conducted with the aim of determining the effect of 8 weeks of TRX training on the levels of homocysteine ​​(Hcy) and nitric oxide (NO) in inactive obese women.

In this quasi-experimental study, 28 obese women with a mean age of 44.34 ±0.82 years were randomly divided into TRX (n = 16) and control (n = 16) groups. The experimental group program consisted of TRX training for eight weeks and three days a week for 50-60 minutes. Serum levels of homocysteine, nitric oxide were measured before and 48 hours after the last training session. Independent and dependent t-tests were used to examine the differences between groups and within-group changes.

After eight weeks of TRX training, comparison results within and between groups are displayed that the mean homocysteine index in the exercise group decreased significantly compared to the control group (p = 0.01). Also, exercise led to an increase in nitric oxide levels in obese women, although this increase was not statistically significant.

Based on the findings of the research, it seems that doing TRX training can be effective as an exercise method in reducing inflammation and improving endothelial function in obese women.