Comparison of the effect of 12 week of endurance training and HIIT on Plasma values of Vaspin in obese male wistar rats
Vaspin is one of the peptide adipocytokines secreted from adipose tissue, which plays a role in the pathogenesis of obesity and related disorders. Vaspin has recently been identified as a new adipocytokine with the effects of increasing insulin sensitivity. There is little information about the effects of exercise on vaspin concentration. The present study has studied the effect of endurance training and HIIT on the plasma concentration of vaspin in obese male wistar rats.
The current research was of a randomized experimental type with a comparison design of two control and experimental groups. 30 rats (mean and standar deviation of weight 200±20 gr and age 8 weeks) were randomly divided into 3 groups: control group, endurance training, and HIIT training. All 3 groups included 10 rats. For 12 weeks, experimental groups did exercises based on exercise programs -three days a week, while the control group had no exercise. Following 12 weeks training, plasma vaspin were measured. 36 hours after the last training session and 10 hours of fasting, the blood samples of rats of all groups were taken directlyfrom the heart after cutting the peritoneal region. The Kruskal-Wallis test was used to compare the average of three research groups and the U-ManWhitney test was used to compare the pairwise averages at a significance level of P≤ 0.05.
After 12 weeks of endurance and HIT training, Vaspin levels, in practice Group endurance and HIT compared with the control group significantly decreased (P=0.001). This study showed both types of endurance training and HIIT, significantly improve Vaspin levels.
According to the results of the present study, it can be stated that endurance training and HIIT can be considered as a solution to reduce fat tissue and adipocytokines, including vaspin and other pro-inflammatory factors.
Adipose tissue , adipocytokine , Exercise , Rat , Vaspin
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