Relationship of Ambiguity Tolerance, Trust, Religious Attitude, and Quality of Life with the Attitude towards COVID-19 Vaccination: Analyzing the Mediating Role of Health Anxiety

This s tudy aimed to inves tigate the relationship of ambiguity tolerance, trus t, religious attitude, and quality of life with the attitudes toward COVID-19 vaccination by analyzing the mediating role of health anxiety among citizens in Zanjan, Iran.

This descriptive-correlational s tudy was conducted on 597 citizens of Zanjan who were selected using the convenience sampling method. The data were collected utilizing the COVID-19 Vaccination Attitude Ques tionnaire, Uncertainty Intolerance Ques tionnaire by Carleton et al. (2007), NEO Revised Five Personality Factors Ques tionnaire by McCree and Cos ta (1985), Religious Commitment Inventory-10 by Worthington et al. (2003), World Health Organization Quality of Life Ques tionnaire (1996), and Health Anxiety Ques tionnaire by Salkowski and Warwick (2002). The obtained data were then analyzed using the Pearson correlation coefficient tes t and path analysis in SPSS software (version 26) and LISREL software (version 10.20).

The s tandard pathway coefficients indicated a significant correlation of the attitude towards the COVID-19 vaccination with ambiguity tolerance (β=-0.09, P˂0.05), trus t (β=-0.10, P˂0.05), and quality of life (β=-0.28, P˂0.001). Moreover, health anxiety was directly correlated with ambiguity tolerance (β=-0.11, P˂0.05), trus t (β=-0.11, P˂0.05), religious attitude (β=-0.12, P˂0.01), and quality of life (β=-0.09, P˂0.05). In addition, the results revealed the indirect association of tolerance of ambiguity, trus t, religious attitude, and quality of life with health anxiety (β=-0.16, P˂0.001).

According to the results, health anxiety can play a mediating role in the relationship of the attitude towards COVID-19 with ambiguity tolerance, trus t, religious attitude, and quality of life.