Evaluation of the Protective Effect of Chrysin on Sperm Parameters on the Process of Spermatogenesis in Rats Receiving Diazinon Toxin

Compounds such as chrysin inhibit the effects of toxic substances such as diazinon on visceral organs and the present study was performed to evaluate the protective effect of chrysin on spermatogenesis by interfering with diazinon toxin. In this experimental study, 42 male Wistar rats weighing approximately 250-180 g were selected and randomly divided into 7 groups including control, sham, diazinon with a concentration of 20 mg/kg BW, chrysin with a concentration of 10, Chrysin with a concentration of 20 mg/kg, chrysin with a concentration of 10 mg/kg and diazinon with a concentration of 20 mg/kg and chrysin with a concentration of 20 mg/kg and diazinon with a concentration of 20 mg/kg were divided. At the end of the treatment period, with the process of tissue preparation, with Motic software, the number of cell lines per unit area was determined and compared with each other in different groups. There was a significant difference between the mean number of sperm count and sperm motility in the Sham and Control groups with Diazinon and DC10 groups (p < 0.001), and DC20 groups (p < 0.01). Also, there was a significant difference in sperm mortality in Shm and Cnt groups with Diazinon, DC10 and DC20 test groups (p < 0.001). The results showed that there was a significant difference in the mean number of sperm count, sperm motility, sperm mortality, sperm morphology, number of Leydig cells, number of germ cells, number of primary and secondary spermatocytes, and number of spermatids in Sham and Control groups compared to some test groups. Thus, CHR as a potent antioxidant can compensate for the toxicity of Diazinon toxin.
 
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