Evaluation of the Efficiency of Catalytic Ozonation Process with magnesium-aluminum double layer hydroxide nanocomposite doped on zeolite in mineralization of cefixime antibiotic in Aqueous Solution

One of the problems in the health systems of the world today is the prescription or overuse of drugs. Among these, antibiotics are of particular importance. Antibiotics are a group of drugs that are widely used in medicine and veterinary medicine. Cefixime (CFX) is also one of these antibiotics. The aim of this study was to investigate the removal efficiency of cefixime from synthetic sample using catalytic ozonation with Mg-Al layered double hydroxides Doped with zeolite.

In this experimental and laboratory study MgAl-LDH/Zeolite nanocomposite was used in laboratory reactor and ozonation to remove cefixime. Effect of pH variables (5,6,7,8,9), amount of nanocomposite (0.5,1,1.5,2,2.5 g/L), initial concentration of cefixime (5,10,15,20,25 mg/L) and reaction time (5,18.75,32.5,46.25,60 min) were examined to find the maximum mineralization efficiency and response surface methodology based on central composite design (CCD) was used to design experiments, analyze data and achieve optimal conditions. Analysis of variance was also used to analyze the date. This research was done in 2021-2022.

The maximum mineralization efficiency of cefixime under optimal conditions (pH=8.70, nanocomposite value=1.76 g/L, initial concentration of cefixime=24.06 mg/L, contact time=40.76 min) is 78%, which increases the target efficiency with increasing pH and contact time.

Catalytic ozonation process with Mg-Al layered double hydroxides nanocomposite Doped with zeolite can be used effectively and efficiency to remove cefixime in aqueous media.