Investigation and Comparison of Hemoglobin A1c Level in Diabetic Patients with and without Lower Limb Amputation

Diabetes is the most common endocrine disease, which has an increasing prevalence in the world and is the most important cause of non-traumatic limb amputation. Amputation is one of the problems that arise in these patients. Based on this, the present study was conducted with the aim of determining and comparing glycosylated hemoglobin between two groups with and without lower limb amputation in patients with diabetic ulcers referred to Shahid Beheshti Hospital in Qom.

This study was a case-control Study, the research population was patients with diabetic ulcers referred to Shahid Beheshti Hospital in Qom in 2018-2019. A total of 262 patients (127 in the group of diabetic patients with amputation and 135 in the group of diabetic patients without amputation) were examined. Finally, all the clinical and paraclinical information of the patients were extracted from the patients' files and were analyzed between the two groups.

There was no significant difference between gender, age and duration of hospitalization in the two groups (P > 0.005) and the two groups were homogeneous, but there was a significant difference between body mass index, hemoglobin A1C and fasting blood sugar in the two groups (P < 0.005) and was higher in the group of patients with diabetes with amputation.

According to our findings, there is a statistically significant difference in blood sugar and hemoglobin A1C as well as body mass index between the two groups with and without amputation. In this regard, it is necessary for patients not only to eat a balanced diet and correct their lifestyle according to the disease, but also to do proper sports.